Kuedzwa kweropa Kunogona Kubatsira Kuona Gomarara Remazamu, Chino Chidzidzo Chazvino

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Gomarara repazamu ndiyo mhando yakajairika yegomarara risiri reganda. Iyo inonzi ndeimwe yemhando dzinowanzozivikanwa dzegomarara dzakabata vanhu, kunyanya mumakore gumi apfuura. MuIndia chete, zvinopfuura miriyoni imwe zviitiko zvekenza yemazamu zvinotaurwa gore rega rega.

Nezve mushumo uchangobva kuitika, kwakapoterera mazana maviri nemakumi maviri nemaviri, mazana manomwe nemakumi manomwe ekuongororwa patsva anotarisirwa mumadzimai, uye kwakatenderedza makumi mana nemazana matanhatu evakadzi vangangofa nechirwere ichi. Gomarara repazamu haisi yevakadzi chete, nekuti inogona kubatawo varume. Vanopfuura vanhu mazana mapfumbamwe nemazana mashanu vanotsvaga kurapwa kwekenza yemazamu gore rega uye vanhu vangangoita chiuru nemazana mashanu vanovhiyiwa gomarara repazamu gore rega rega ^[1] .

Gomarara repazamu rinokura apo masero emuzamu anotanga kukura zvisina kujairika, ayo anobva awanda nekukurumidza kupfuura maseru ane hutano uye achiramba achiwanda, zvichikonzera kukura kwesumbu kana bundu. ^[piri] . Kazhinji, kenza yemazamu yakaonekwa kana chiratidzo kana chiratidzo chikamuka uye chikaongororwa nerubatsiro rweyedzo uye maitiro senge bvunzo yemazamu, mammogram , zamu ultrasound nezvimwe.

Nekudaro, ongororo ichangoburwa yakati kuongororwa kweropa kwenyowani kunogona kubatsira mukutanga kuona kenza yemazamu.

Ropa Rinoedzwa Rinogona Kubatsira Kutsvaga Gomarara Rezamu Makore mashanu Asati Aonekwa Zviratidzo

Imwe yenjodzi huru nematambudziko kana zvasvika kugomarara kunonoka kuonekwa. Kana mamiriro acho apararira kune dzimwe nzvimbo, mwero wekupona wakanyanya kuderera nemikana yekudzokazve ^[3] .

Nekudaro, kuona kwekutanga uye kurapwa kunoshanda kunogona kubatsira kusimudzira huwandu hwekufa. Asi kana iri nyaya yekenza yemazamu, kutanga kwekuonekwa kwechisikirwo kune mashoma sezvo hakuwanzo kuburitsa pachena zviratidzo padanho rekutanga, izvo zvinogona kutungamira kukurumidza kunonoka kunogona kukanganisa kugona kwekurapa.

Mune ongororo ichangoburwa yakaitwa nevatsvagiri vepaUniversity yeNottingham kuUnited Kingdom vakasimbisa kuti kuongororwa kweropa kunoongorora kuti kune mamwe ma antibodies kunogona kubatsira kuona gomarara repazamu nekukurumidza uye nyore. ^[4] .

Iyo Bvunzo Inogona Kuona Autoantibodies

Vatsvakurudzi vakaenderera mberi nekutsanangura mashandiro ekuongororwa kweropa nekutsanangura kuti kana gomarara riripo, muviri wako unoburitsa maantigen anounza mhinduro yemumuviri. Izvi, zvakare, zvinoita kuti immune system iite kune izvo zvinhu nekusunungura autoantibodies, iyo inozoonekwa nekuongororwa kweropa uye kuratidza kana gomarara repazamu riripo kana kwete.

Pakutanga, ivo vaongorori vakagadzira mapaneru emota-inosanganisirwa maantigen (TAAs) yakanangana nekenza yemazamu iyo yakabatsira mukunzwisisa kuvepo kwema autoantigener muropa ayo anofambidzana nemhinduro kune kenza yemazamu-yakatarwa TAAs ^[5] .

Mumwe wevaongorori Daniyah Alfattani akati, 'Mhedzisiro yechidzidzo chedu yakaratidza kuti kenza yemazamu inokonzeresa maantiantibodies kurwisa mapaneru eanosangana nemaantigen. Isu takakwanisa kuona gomarara nekururamisa zvine mutsindo nekutsanangudza izvi autoantibodies muropa ', uye takasimbisawo pakukosha kwekuvandudza nekusimbisa kuongororwa kweropa. ^[6] .

Kudzidza Kunoratidza Kunovimbisa Mhedzisiro

Vatsvagiri vanofara nemhedzisiro yechidzidzo nekuti mhedzisiro yacho inokurudzira uye inoratidza kuti zvinokwanisika kuona chiratidzo chekenza yemazamu yekutanga. 'Kana tangovandudza chokwadi chebvunzo, zvino inovhura mukana wekushandisa ongororo yeropa kuti uvandudze chirwere', akadaro muongorori zvakanaka ^[6] .

Chidzidzo chiine vanodarika makumi mapfumbamwe vakapindura, zvinogona kufungidzirwa kuti mhedzisiro yacho inechokwadi zvine mutsindo uye kuongororwa kweropa kwenyanzvi kunogona kubatsira mukubatsira nyanzvi dzekurapa uye vanachiremba vanoona kuvepo kwekenza yemazamu kusvika pamakore mashanu zvisati zvaonekwa zviratidzo.

Pane Yekupedzisira Chiziviso ...

Nechidzidzo ichi chichiburitsa mimwe mibairo yakanaka, vatsvagiri vari kuwedzera nzvimbo yekudzidza nekuti kuongororwa kweropa kuongororwa kwekutanga kwekenza yemazamu kunodhura, uyezve kunobatsira uye nenzira dziri nyore dzekuongorora kana tichienzanisa matanho aripo ^[7] . Miedzo yakafanana iri mukusimudzira kwemamwe marudzi ekenza, kusanganisira mapapu, pancreatic, colorectal, uye kenza yechiropa.

1. [1]Lauren, S. & Cassell, M. Kuvhiya kwemazamu, Lenox Hill Hospital, New York City Alice Mapurisa, MD, Westchester director wedunhu, kuvhiya kwemazamu, Northwell Health Cancer Institute, Sleepy Hollow, NY NCRI (National Cancer Research Institute, UK), kuburitswa kwemashoko, Mbudzi 2, 2019
2. [piri]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). U.S. Patent Chikumbiro Nha. 15 / 564,089.
3. [3]Spadafora, C., Sciamanna, I., De Luca, C., Sinibaldi-Vallebona, P., Guadagni, F., Schumann, G., & Garaci, E. (2019). U.S. Patent Chikumbiro Nha. 10 / 214,591.
4. [4]Yadav, S., Kashaninejad, N., Masud, M. K., Yamauchi, Y., Nguyen, N. T., & Shiddiky, M. J. (2019). Autoantibodies sekuongorora uye kufungidzira cancer cancer biomarker: Maitiro ekutsvaga uye nzira. Biosensors uye Bioelectronics, 111315.
5. [5]Jiang, XH, Yao, Z. Y., Iye, X., Zhang, J. B., Xie, K., Chen, J., ... & Yie, S. M. (2019). Clinical kukosha kweplasma anti-TOPO48 autoantibody uye neropa rinopona-kuratidza kutenderera maseru emukenza mune varwere vane yekutanga danho endometrial carcinoma. Zvinyorwa zvegynecology uye obstetrics, 299 (1), 229-237.
6. [6]Seluk, L., Taliansky, A., Yonath, H., Gilburd, B., Amital, H., Shoenfeld, Y., & Kivity, S. (2019). Screen hombe yeparaneoplastic neurological autoantibodies kuongororwa uye hunhu hwekufungidzira. Clinical Immunology, 199, 29-36.
7. [7]Khayeka-Wandabwa, C., Ma, X., Cao, X., Nunna, V., Pathak, J. L., Bernhardt, R., ... & Bureik, M. (2019). Plasma membrane localization yeCYP4Z1 uye CYP19A1 uye kuonekwa kweanopikisa-CYP19A1 autoantibodies muvanhu. Yepasi rose immunopharmacology, 73, 64-71.

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