L-carnitine: Kubatsira kwayo, Zvinyorwa uye Nezvakakomba Mhedzisiro

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L-carnitine iamino acid, inogadzirwa zvakasikwa mumuviri. Iyo amino acid inogadzirwa inowanzo kudyiwa yekuwedzera. Izvo zvinovaka muviri zvinoita basa rakakosha mukugadzirwa kwesimba mumuviri wako. Nekutakura mafuta acids mumuviri wako kune mitochondria, inovawo, inobatsira kupisa mafuta uye kuishandura kuita simba.

L-carnitine inogadzirwa mukati memuviri wako, iyo inogadzirwa kubva kune amino acids lysine uye methionine. Kuti muviri wako ubudise huwandu hunodiwa hweL-carnitine, unofanirwa kunge uine huwandu hwakawanda hwevitamini C. Kunze kwaizvozvo, L-carnitine inogona kuwanikwa mune zvidiki nekudya chikafu senyama, mukaka, hove nezvimwe. inowanikwawo nenzira yekuwedzera ^{[1] [piri]} .

Iyo amino acid ndiyo yakajairwa biologically inoshanda fomu ye carnitine (zita regeneti reiyo quaternary ammonium komputa inobatanidzwa mune metabolism mune zvipuka, zvirimwa uye mamwe mabhakitiriya), iyo inowanikwawo muchimiro cheD-carnitine, Acetyl-L-carnitine, Propionyl-L-carnitine, uye L-carnitine L-tartrate ^[3] .

Hutano Makomborero E-L-carnitine

1. Aids kuonda

L-carnitine yakasimuka ikaita mukurumbira munguva dzichangopfuura nekwanisiro yayo yekubatsira kuonda. Iyo amino acid yekuwedzera inoshanda nekutakura mafuta acids mumasero ako, ayo anozopiswa kuita simba. Kunyangwe paine kupokana pane kugona kwekuwedzera kwekusimudzira kurasikirwa kwehuremu, ongororo yakaitwa kune vanhu vakafutisa yakatsigira chirevo chekuti L-carnitine inobatsira kurasikirwa nekurema ^[4] .

2. Inovandudza kushanda kwehuropi

Zvimwe zvidzidzo zvakaratidza kuti L-carnitine inogona kubatsira kuvandudza mashandiro ehuropi hwako. Ndokunge, zvinogona kubatsira kudzivirira kukanganisika kwepfungwa zvine chekuita nezera, kubatsira kuvandudza kugona kwemunhu kudzidza, uye kubatsira kudzosera kudzikira kwehuropi basa kudzivirira kutanga kweAlzheimer's uye zvimwe zvirwere zvehuropi ^[5] .

3. Inotarisira hutano hwemwoyo

L-carnitine yave ichibatanidzwa nekuderedza kuwedzera kweropa uye iyo yekuzvimba nzira inosangana nechirwere chemwoyo. Izvo zvakare zvakasimbiswa kuve nekwaniso yekuvandudza mamiriro evanhu vanotambura neakanyanya moyo kusagadzikana, senge coronary chirwere chemoyo uye chisingaperi moyo kutadza. ^[6] .

4. Kunowedzera kuita

Zvidzidzo zvakasiyana zvakaratidza mabhenefiti, kunyange ari madiki, L-carnitine ine pamusoro pekuvandudza mashandiro emitambo. Nekuda kweichi chivakwa, L-carnitine izita rakajairika munhandare yemitambo. Zvinogona kubatsira kuvandudza yako kurovedza muviri kupora, kuwedzera okisijeni kuendesa kune tsandanyama dzako, kunatsiridza kusimba kwako, kudzikisa tsandanyama kusuruvara uye kuwedzera tsvuku reropa reropa kugadzirwa. ^[3] .

5. Kudzora chirwere cheshuga

L-carnitine inogona kukubatsira kubata uye kudzikisa zviratidzo zvechirwere cheshuga, kunyanya rudzi rwechipiri chirwere cheshuga. Izvo zvinobatsirawo kugadzirisa zvinenjodzi zvemamiriro acho, sezvo amino acid inogona kubatsira kudzikisa mashuga eropa ^[6] .

Zvinonzi zvakare zvinobatsira pakupa zororo kubva pakurwadziwa pachipfuva, hosha yeitsvo, hyperthyroidism, kushaya mbereko kwevanhurume, acne, kurasikirwa nevhudzi, autism, kurova kwemoyo zvisina kujairika, tsinga dzakavharika, kuneta, huremu hwekuzvara uye zvimwe zvakasiyana. Nekudaro, pane kushomeka kwezvidzidzo pane zvakawedzerwa kushanda uye kushanda kweL-carnitine pamamiriro akasiyana ^[7] .

Side Migumisiro YeL-carnitine

Iyo L-carnitine inowedzera kana majekiseni, kunyangwe yakachengeteka kushandiswa kwevanhu, inogona kukonzera mhedzisiro-mhedzisiro mune vamwe vanhu. Mimwe yemhedzisiro mhedzisiro yemamino acid inotaurwa pazasi ^[8] .

• Nausea
• Kusvipa
• Dumbu kurwadziwa
• Kushungurudza
• Manyoka
• Kufenda
• Hove hwehove mumurini, mweya uye ziya

Kunze kwaizvozvo, vakadzi vane pamuviri uye vanoyamwisa vanofanirwa kudzivirira kushandisa L-carnitine ^[9] . Kuwedzeredza L-carnitine kunogona kukonzera itsvo kutadza, pamwe nekuwedzera zviratidzo zvehypothyroidism. Zvakare, dzivisa kunwa L-carnitine yekugadzirisa kubatwa, kana iwe watotambura nekubatwa kare.

Chipimo chemushonga weL-carnitine

Ongorora: Unofanirwa kubvunza nachiremba usati waisa L-carnitine zvinowedzera kana majekiseni mumaitiro ako.

Muyero unotaurwa pano ndewevanhu vakuru ^[10] .

L-carnitine kushomeka: 990 mg, kaviri kana katatu pazuva (mapiritsi kana mhinduro yemumuromo).

Kurwadziwa pachifuva: 900 mg kusvika 2 g mu1 kusvika 2 akapatsanurwa madosi zuva rega rega kwevhiki mbiri kusvika kumwedzi mitanhatu.

Muyero wakajairika weL-carnitine ndeye 500-2,000 mg pazuva.

Pane Yekupedzisira Chiziviso ....

Kune vegans, kuburitsa pamwe nekuwana L-carnitine kunogona kusakwanisika nekuda kwekushaikwa kwenyama nehove kushandiswa. Izvozvowo zvinoenda kune vanhu vanotambura kubva kune mamwe magene. Zvisinei, munhu anogona kuwana huwandu hunodiwa hweL-carnitine nekushandisa L-carnitine zvinowedzera.

1. [1]Kumisikidza, R., Riede, L., Lugo, J., & Bellamine, A. (2018). l-Carnitine yekuwedzeredza mukudzoreredza mushure mekurovedza muviri. Nutrients, 10 (3), 349.
2. [piri]Koeth, R.A, Lam-Galvez, B. R., Kirsop, J., Wang, Z., Levison, B. S., Gu, X., ... & Culley, M.K (2018). l-Carnitine mune zvekudya zvinodyisa zvinoita kuti atherogenic gut microbial nzira muvanhu. Zvinyorwa zveKiriniki Kuferefeta, 129 (1), 373-387.
3. [3]Novakova, K., Kummer, O., Bouitbir, J., Stoffel, S. D., Hoerler-Koerner, U., Bodmer, M., ... & Krähenbühl, S. (2016). Mhedzisiro ye l-carnitine yekuwedzera pane iyo muviri carnitine dziva, skeletal mhasuru simba metabolism uye kuita kwemuviri mune vechirume vezvirimwa. Magazini yeEuropean yezvokudya zvinovaka muviri, 55 (1), 207-217.
4. [4]Lee, B. J., Lin, J. S., Lin, Y. C., & Lin, P. T. (2015). Antiinfigueatory mhedzisiro yeL-carnitine yekuwedzera (1000 mg / d) mune coronary artery chirwere varwere. Nutrition, 31 (3), 475-479.
5. [5]Chan, Y. L., Saad, S., Al-Odat, I., Oliver, B. G., Pollock, C., Jones, N. M., & Chen, H. (2017). Maternal L-carnitine yekuwedzera inovandudza hutano hwehuropi muvana kubva muhutsi hwefodya hwakafumurwa vanaamai Vanotungamira vema molecular neuroscience, 10, 33.
6. [6]Fukami, K., Yamagishi, S. I., Sakai, K., Kaida, Y., Yokoro, M., Ueda, S., ... & Okuda, S. (2015). Oral L-carnitine yekuwedzera inowedzera trimethylamine-N-oxide asi inoderedza mamaki ekukuvara kwevascular muvarwere vehemodialysis.Journal yemoyo wemashemia pharmacology, 65 (3), 289-295.
7. [7]da Silva, G. S., de Souza, C. W., da Silva, L., Maciel, G., Huguenin, A. B., de Carvalho, M., ... & Colafranceschi, A. (2017). Mhedzisiro yeL-Carnitine Supplementation pane Reverse Remodeling muvarwere vane Ischemic Moyo Chirwere Chiri Kupfuura Coronary Artery Bypass Kunyorerana: Randomized, Placebo-Inodzorwa Trial.
8. [8]Lee, B. J., Lin, J. S., Lin, Y. C., & Lin, P. T. (2016). Mhedzisiro yeL-carnitine yekuwedzera pane lipid profiles mune varwere vane coronary arteri chirwere. Lipids mune hutano uye chirwere, 15 (1), 107.
9. [9]Pala, R., Genc, ​​E., Tuzcu, M., Orhan, C., Sahin, N., Er, B., ... & Sahin, K. (2018). L-Carnitine yekuwedzera inowedzera kutaura kwePPAR-γ uye glucose vatakuri mumasaga emhasuru yemakonzo asingagumi uye akasimba.Cellular uye molecular biology (Noisy-le-Grand, France), 64 (1), 1-6.
10. [10]Imbe, A., Tanimoto, K., Inaba, Y., Sakai, S., Shishikura, K., Imbe, H., ... & Hanafusa, T. (2018). Mhedzisiro yeL-carnitine yekuwedzera pane iwo hupenyu hwehupenyu mune vane chirwere cheshuga varwere vane mhasuru cramp. Endocrine magazini, EJ17-0431.

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