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Dzinobuda nenjodzi dzeCOVID-19 dzinosanganisira zera, murume kana murume, BP, chirwere cheshuga uye kufuta. Munguva pfupi yapfuura, humwe humbowo hwekiriniki uye zvidzidzo zvakaratidza kusangana kunogona kuitika pakati pePCOS neCOVID-19.
Zvidzidzo izvi zvinoti vakadzi vanotambura ne polycystic ovary syndrome (PCOS) kana polycystic ovarian chirwere (PCOD) vanogona kunge vari panjodzi yekuwedzera kwehutachiona hweCOVID-19 zvichienzaniswa nevakadzi vasina PCOS. Ichi chinyorwa chichataura kuti sei uye nei zvichikwanisika. Verenga pamusoro kuti uzive zvakawanda.
COVID-19 Uye Vakadzi Vanotambura Kubva kuCPOS
Zvinoenderana neongororo yakaburitswa muEuropean Zvinyorwa zveEndocrinology, vakadzi vane PCOS vari pamakumi masere nemasere muzana njodzi yekuwedzera kutapukirwa neCOVID-19 ichienzaniswa nevakadzi vasina mamiriro. Mhedzisiro yacho yakaverengerwa mushure mekugadzirisa zera, BMI uye njodzi yenjodzi. [1]
Pasina shanduko dzambotaurwa, ongororo yakanga yaratidza kuti vakadzi vePCOS vari pamakumi mashanu nechimwe muzana panjodzi yepamusoro yeCOVID-19 pakati pevakadzi vasina PCOS.
Nei PCOS Varwere Vari Pakuwedzera Njodzi yeCOVID-19?
Kubva nhasi, COVID-19 yakabata vanhu vangangosvika mamirioni gumi nemaviri pasi rose, nemamiriyoni 70.1 akadzorerwa kesi uye kufa kwemamirioni 2.72. Zvakawanda zvakaburitswa zvidzidzo zvakaratidza kuti rabhoritari-yakasimbiswa COVID-19 kesi dzakanyanya kuwanda muvanhurume munyika dzinoverengeka zvichienzaniswa nevakadzi.
Kunyangwe hazvo chikonzero chiri chakasiyana-siyana, mhedzisiro ye androgen hormone inoonekwa seimwe yezvikonzero zvakakosha zvekusiyana-kwepabonde musiyano muhutachiona hwehutachiona.
Androgen inonyanya kutaurwa sehomoni yechirume iyo inotonga kusimudzira uye kugadzirisa kwehunhu hwechirume uye zviitiko zvavo zvekubereka. [piri]
Iyo hormone iriko, zvakadaro, irimo mune vese varume nevakadzi, asi chikuru chayo basa ndechekusimudzira testosterone uye androstenedione, maviri eanoverengeka echirume echikadzi mahormone.
PCOS chirwere che endocrine umo makero e androgens (echirume mahormone) anokwira kumusoro, pachinzvimbo cheestrogen (mukadzi mahormone). Izvi zvinotungamira ku hyperandrogenism uye ovarian dysfunction, zvichikonzera kushaya mbereko mune vamwe vasina kunyatso kuongororwa uye kurapwa.
Sezvo iyo uyerogen hormone inoonekwa sechinhu chakakosha panjodzi yekutapukirwa neCOVID-19, zvinogona kutaurwa kuti vakadzi vePCOS vanogona kuwedzera kusangana nechirwere ichi, tichifunga kuti zvimwe zvinhu zvakaita sekufutisa muvakadzi vePCOS zvinogona zvakare kunge zviri izvo chikonzero.
Zvimwe Zvinhu
1. Insulin kuramba
PCOS yakabatana nematambudziko emagetsi senge insulin kudzivisa uye chirwere cheshuga. Insulin ihormoni inobatsira kubata mazinga eglucose mumuviri, pamwe nekudzora metabolism yemapuroteni uye lipids.
Insulin kuramba inovandudzwa kana muviri ukasapindura insulin, zvichikonzera kusashandiswa kweshuga muropa kune simba, zvichikonzera kuwedzerwa kweropa glucose. Kuwedzera kweglucose kunotanga kupindirana nemaseru ekudzivirira akadai seB masero, macrophage uye T maseru, zvichikonzera kudzikira kwema immune immune.
Kusashanda zvakanaka kwe immune system nekuda kweiyo insulin kudzivisa, iyo yakatanga nekuda kwePCOS inogona kupedzisira yati nei vakadzi vane PCOS vari kubatwa zvakanyanya necoronavirus. [3]
2. Kufutisa
Tsvagiridzo yakaratidza kuti munguva pfupi yapfuura kubuda kwecoronavirus, pakati pevanhu vaive nemhepo, chiyero chevarwere vakafutisa chaive chakakwirira, kuchiteverwa nekuwedzera kwehuwandu hwekufa pakati pevanhu ava. [4]
Chimwe chidzidzo chakajekesawo chokwadi chekuti panguva yechirwere chekare cheH1N1 hutachiona kana chirwere chenguruve, kuomarara kwemamiriro acho kwaive kwakanyanya muvanhu vakafutisa. [5]
Dzakakomberedza 38-88 muzana yevakadzi vane PCOS vanowanikwa vakafutisa kana kufutisa. Hukama hwepedyo pakati pekufutisa, PCOS uye COVID-19 hunogona kupedzisa, kuti vakadzi vePCOS vanogona kubatwa neCOVID-19 nekuda kwekunyanyisa kana kufutisa.
3. Kushayikwa kweVitamin D
Kushomeka kweVitamin D kwakabatana nePCOS uye COVID-19 hutachiona munzira dzakawanda. Vitamin D yakakosha vhitamini iyo inogona kubatsira kudzivirira kufema kutapukirwa kweCOVID-19 neayo immune-inowedzera pfuma uye kudzikisira kupisa cytokines kunotungamira kubayo.
Munzvimbo dzakatenderedza 67-85 muzana yevakadzi vane PCOS, kushomeka kwakanyanya kwevhitamini D kwave kuchionekwa. [6]
Kushaikwa kwevhitamini D kunogona kukonzera kusagadzikana kwema immune, kuwedzerwa kwekuzvimba cytokines uye kuwedzera njodzi yekusagadzikana senge chirwere cheshuga, insulin kudzivisa uye kufutisa, matambudziko ese ePCOS.
Naizvozvo, zvinogona kutaurwa kuti kushomeka kwevhitamini D kunogona kusanganiswa nePCOS uye nekuwedzera matambudziko uye mwero wekufa nekuda kweCOVID-19.
4. Zvakanaka microbiota
Gut dysbiosis kana kusagadzikana kwegumbo microbiota inosangana nemamiriro ehutano senge PCOS.
PCOS uye gut gut hutano zvinofambidzana. Vakadzi vane PCOS vanowanzo kuwanikwa vaine gut dysbiosis. Nekudaro, kana iwo mashuga shuwa akakwenenzverwa mushe uye gadziriro yekugaya ichichengetwa muPCOS, hutano hwemuviri hunogona kuvandudzwa.
Shanduko mukuumbwa kweiyo gut microbiome inogona kukanganisa immune system, iyo yekutanga system yemuviri inotidzivirira kubva kuzvirwere uye nekudaro, inoita kuti isu titarise hutachiona senge COVID-19.
Iko kushandiswa kwemaantibioti kuchengetedza muyero wematumbo microbiota kunogona kubatsira kusimbisa hutachiona uye kudzivirira njodzi ye COVID-19.
Kupedza
Insulin kuramba kunogona kuwedzera kugadzirwa kwe androgens mune vakadzi vane PCOS. Kufutisa uye kufutisa kunogona kukuvadza insulin kusagadzikana uye nekudaro, kuwedzera kugadzirwa kwe androgen. Izvi zvinogona kukonzera kusagadzikana kwema immune system nekuda kweiyo endocrine-immune axis, iyo inogona ipapo, kuwedzera njodzi yeCOVID-19 mumadzimai ePCOS.
